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Perfluorocarbon‐Loaded Hollow Bi<sub>2</sub>Se<sub>3</sub> Nanoparticles for Timely Supply of Oxygen under Near‐Infrared Light to Enhance the Radiotherapy of Cancer

Guosheng Song, Chao Liang, Xuan Yi, Qi Zhao, Liang Cheng, Kai Yang, Zhuang Liu

2016Advanced Materials589 citationsDOI

Abstract

Hollow Bi2Se3 nanoparticles prepared by a cation exchange method are loaded with perfluorocarbon as an oxygen carrier. With these nanoparticles, a promising concept is demonstrated to enhance radiotherapy by not only using their X-ray-absorbing ability to locally concentrate radiation energy in the tumor, but also employing near-infrared light to trigger burst release of oxygen from the nanoparticles to overcome hypoxia-associated radio-resistance. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Topics & Concepts

Materials scienceInfraredNanoparticleNanotechnologyOxygenOptoelectronicsChemical engineeringOpticsOrganic chemistryEngineeringPhysicsChemistryNanoplatforms for cancer theranosticsLuminescence Properties of Advanced MaterialsElectronic and Structural Properties of Oxides
Perfluorocarbon‐Loaded Hollow Bi<sub>2</sub>Se<sub>3</sub> Nanoparticles for Timely Supply of Oxygen under Near‐Infrared Light to Enhance the Radiotherapy of Cancer | Litcius