Synthesis of indole-based-thiadiazole derivatives as a potent inhibitor of α-glucosidase enzyme along with in silico study
Munther Alomari, Muhammad Taha, Fazal Rahim, Manikandan Selvaraj, Naveed Iqbal, Sridevi Chigurupati, Shafqat Hussain, Nizam Uddin, Noor B. Almandil, Muhammad Nawaz, Rai Khalid Farooq, Khalid Mohammed Khan
Topics & Concepts
AcarboseChemistryIndole testIC50StereochemistryIn silicoEnzyme kineticsEnzymeDocking (animal)KineticsCarbon-13 NMRInhibitory postsynaptic potentialActive siteIn vitroBiochemistryPhysicsQuantum mechanicsBiologyGeneNursingNeuroscienceMedicineNatural Antidiabetic Agents StudiesSynthesis and biological activityPsidium guajava Extracts and Applications