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A data-driven sequencer that unveils latent “codons” in synthetic copolymers

Yusuke Hibi, Shiho Uesaka, Masanobu Naito

2023Chemical Science14 citationsDOIOpen Access PDF

Abstract

Codons in synthetic copolymers—sequence-specific short segments encoding synthetic copolymer properties—became quantifiable via thermal fragmentation and virtual reconstruction based on unsupervised learning of pyrolysis mass-spectra.

Topics & Concepts

CopolymerPolymerMonomerTernary operationSequence (biology)Stop codonBinary numberTemplateChemistryComputational biologyComputer scienceMaterials scienceNanotechnologyBiologyMathematicsGeneBiochemistryOrganic chemistryProgramming languageArithmeticChemical Synthesis and AnalysisMass Spectrometry Techniques and ApplicationsMachine Learning in Materials Science
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