Mechanism of hepatobiliary toxicity of the LPA1 antagonist BMS-986020 developed to treat idiopathic pulmonary fibrosis: Contrasts with BMS-986234 and BMS-986278
Michael Gill, Brian J. Murphy, Peter T. W. Cheng, Lakshmi Sivaraman, Myrtle Davis, Lois D. Lehman‐McKeeman
Topics & Concepts
PharmacologyToxicityChemistryEffluxIC50ATP-binding cassette transporterTransporterBiochemistryMedicineIn vitroOrganic chemistryGeneDrug Transport and Resistance MechanismsInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisLiver physiology and pathology