Astragaloside IV regulates the ferroptosis signaling pathway via the Nrf2/SLC7A11/GPX4 axis to inhibit PM2.5-mediated lung injury in mice
Xiaoming Wang, Yilan Wang, Demei Huang, Shihua Shi, Caixia Pei, Yongcan Wu, Zherui Shen, Fei Wang, Zhenxing Wang
Topics & Concepts
Bronchoalveolar lavageOxidative stressPharmacologyGlutathioneReactive oxygen speciesWestern blotChemistryLipid peroxidationAstragalusMedicineLungImmunologyInternal medicinePathologyBiochemistryTraditional Chinese medicineEnzymeAlternative medicineGeneFerroptosis and cancer prognosisSelenium in Biological SystemsImmune cells in cancer