Poly (ethylene glycol)-block-poly (D, L-lactide) (PEG-PLA) micelles for brain delivery of baicalein through nasal route for potential treatment of neurodegenerative diseases due to oxidative stress and inflammation: An in vitro and in vivo study
Zhang Li, Shili Yang, Lizhen Huang, Paul C. Ho
Topics & Concepts
PharmacologyNeuroprotectionOxidative stressNasal administrationEthylene glycolChemistryBioavailabilityInflammationMicelleBaicaleinInhalationToxicityPharmacokineticsBlood–brain barrierIn vivoMedicineBiochemistryImmunologyAnesthesiaCentral nervous systemEndocrinologyBiologyPhysical chemistryAqueous solutionBiotechnologyOrganic chemistryFlavonoids in Medical ResearchPhytochemistry and Biological ActivitiesSaffron Plant Research Studies