α-Santalol functionalized chitosan nanoparticles as efficient inhibitors of polo-like kinase in triple negative breast cancer
Jinku Zhang, Yanan Wang, Jinmei Li, Wenming Zhao, Zhao Yang, Yanguang Feng
Abstract
. Taken together, the α-santalol functionalized chitosan NPs hold great potential in biomedical applications, especially cancer theranostics, due to their versatile nature as well as diagnostics for clinical tumor biology.
Topics & Concepts
ChitosanTriple-negative breast cancerKinaseNanoparticleBreast cancerPolo-like kinaseChemistryCancerNanotechnologyCancer researchCombinatorial chemistryMaterials scienceMedicineBiochemistryInternal medicineCell cycleMicrotubule and mitosis dynamicsGlycosylation and Glycoproteins ResearchAdvanced biosensing and bioanalysis techniques