Exosomes from TNF-α preconditioned human umbilical cord mesenchymal stromal cells inhibit the autophagy of acinar cells of severe acute pancreatitis via shuttling bioactive metabolites
Zhilong Ma, Wangcheng Xie, Tingyi Luo, Zhengyu Hu, Jie Hua, Jia Zhou, Tingsong Yang, Wei Wang, Zhenshun Song, Xianjun Yu, Jin Xu, Si Shi
Topics & Concepts
Mesenchymal stem cellAutophagyMicrovesiclesStromal cellPI3K/AKT/mTOR pathwayExosomeCancer researchPharmacologyChemistryInflammationCell biologyAcute pancreatitisImmunologyBiologyMedicineApoptosisBiochemistrySignal transductionInternal medicinemicroRNAGenePancreatitis Pathology and TreatmentExtracellular vesicles in diseasePhagocytosis and Immune Regulation