ctDNA Monitoring for Small Cell Lung Cancer: Ready for Prime Time?
Bruna Pellini, Aadel A. Chaudhuri
Abstract
Small cell lung cancer (SCLC) is the deadliest form of lung cancer and has few precision medicine approaches available. A recent study analyzed circulating tumor DNA (ctDNA) in 33 patients with extensive-stage SCLC and showed that ctDNA levels and response patterns correlate strongly with clinical response and survival outcomes. See related article by Sivapalan et al., p. 2310.
Topics & Concepts
Lung cancerOncologyMedicineCirculating tumor DNAInternal medicineStage (stratigraphy)CancerCancer researchPathologyBiologyPaleontologyLung Cancer Research StudiesCancer Genomics and DiagnosticsLung Cancer Treatments and Mutations