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Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues

Martina Wallace, Courtney R. Green, Lindsay S. Roberts, Yujung Michelle Lee, Justin L. McCarville, Joan Sánchez-Gurmaches, Noah Meurs, Jivani M. Gengatharan, Justin D. Hover, Susan A. Phillips, Theodore P. Ciaraldi, David A. Guertin, Pedro Cabrales, Janelle S. Ayres, Daniel K. Nomura, Rohit Seth Loomba, Christian M. Metallo

2018Nature Chemical Biology228 citationsDOIOpen Access PDF

Topics & Concepts

LipogenesisCatabolismAdipose tissueFatty acid synthaseBiochemistryBiologyFatty acid synthesisMetabolismEnzymeFatty acid metabolismChemistryMetabolomics and Mass Spectrometry StudiesAdipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors
Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues | Litcius