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Predictive modeling by deep learning, virtual screening and molecular dynamics study of natural compounds against SARS-CoV-2 main protease

Tanuja Joshi, Tushar Joshi, Hemlata Pundir, Priyanka Sharma, Shalini Mathpal, Subhash Chandra

2020Journal of Biomolecular Structure and Dynamics53 citationsDOIOpen Access PDF

Abstract

). From this study, we can suggest that the identified natural compounds may be considered for therapeutic development against the SARS-CoV-2.Communicated by Ramaswamy H. Sarma.

Topics & Concepts

Virtual screeningCoronavirus disease 2019 (COVID-19)Mean squared errorSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Mean absolute errorMolecular dynamicsDeep learningProteaseArtificial intelligenceMachine learningChemistryComputer scienceInfectious disease (medical specialty)MedicineMathematicsStatisticsEnzymeBiochemistryComputational chemistryDiseasePathologyComputational Drug Discovery MethodsDiverse Scientific Research StudiesMachine Learning in Bioinformatics
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