Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains
Thomas E. Speltz, Z. Qiao, Colin Swenson, Xianghang Shangguan, John S. Coukos, Christopher Lee, Deborah Thomas, Jesse Santana, Sean W. Fanning, Geoffrey L. Greene, Raymond E. Moellering
Topics & Concepts
RepressorTranscription factorDNAComputational biologyBiologyGeneDNA-binding proteinDNA-binding domainTranscription (linguistics)Cell biologyGeneticsLinguisticsPhilosophyAdvanced biosensing and bioanalysis techniquesChemical Synthesis and AnalysisProtein Degradation and Inhibitors