Potential mechanisms underlying inhibition of xenograft lung cancer models by kaempferol: modulation of gut microbiota in activating immune cell function
Maoying Guan, Weijie Xu, Haoran Bai, Zixiang Geng, Zhihua Yu, Hegen Li, Te Liu
Abstract
Kaempferol can inhibit xenograft lung cancer models. Such inhibition effect might come from the activation of T cells, NK cells, and other immune cells which are modulated by the gut microbiota.
Topics & Concepts
Immune systemKaempferolMicrobiologyIn vivoCytotoxic T cellLung cancerGut floraBiologyBacteroides fragilisCancer researchImmunologyPharmacologyIn vitroFlavonoidMedicineAntibioticsPathologyBiochemistryAntioxidantBiotechnologyGut microbiota and healthMycobacterium research and diagnosisHelicobacter pylori-related gastroenterology studies