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Optimization of the quality by design approach for gene therapy products: A case study for adeno-associated viral vectors

Toshimitsu Tanaka, Hideki Hanaoka, Shingo Sakurai

2020European Journal of Pharmaceutics and Biopharmaceutics27 citationsDOI

Topics & Concepts

Quality by DesignAdeno-associated virusCritical quality attributesGenetic enhancementIdentification (biology)Computer scienceComputational biologyQuality (philosophy)Process (computing)Vector (molecular biology)Biochemical engineeringRecombinant DNABiologyGeneEngineeringGeneticsDownstream (manufacturing)Operations managementOperating systemEpistemologyBotanyPhilosophyViral Infectious Diseases and Gene Expression in InsectsVirus-based gene therapy researchCAR-T cell therapy research
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