Key molecular DNA damage responses of human cells to radiation
Chengchen Zhang, Jibin Liu, Jun Wu, Kamakshi Ranjan, Xiaopeng Cui, Xingdan Wang, Dianzheng Zhang, Shudong Zhu
Abstract
Our understanding of the DNA damage responses of human cells to radiation has increased remarkably over the recent years although some notable signaling events remain to be discovered. Here we provide a brief account of the key molecular events of the responses to reflect the current understanding of the key underlying mechanisms involved.
Topics & Concepts
DNA damageKey (lock)BiologyDNACell biologyComputational biologyNeuroscienceGeneticsEcologyDNA Repair MechanismsCarcinogens and Genotoxicity AssessmentEffects of Radiation Exposure