Litcius/Paper detail

Emerging roles for AQP in mammalian extracellular vesicles

Charlotte Clarke-Bland, Roslyn M. Bill, Andrew Devitt

2021Biochimica et Biophysica Acta (BBA) - Biomembranes26 citationsDOIOpen Access PDF

Abstract

Recent research in the aquaporin (AQP) field has identified a role for diverse AQPs in extracellular vesicles (EV). Though still in its infancy, there is a growing body of knowledge in the area; AQPs in EV have been suggested as biomarkers for disease, as drug targets and show potential as therapeutics. To advance further in this field, AQPs in EV must be better understood. Here we summarize current knowledge of the presence and function of AQPs in EV and hypothesise their roles in health and disease.

Topics & Concepts

Extracellular vesiclesExtracellularFunction (biology)DiseaseBiologyCell biologyNeuroscienceMedicineInternal medicineExtracellular vesicles in diseaseMicroRNA in disease regulationSolar-Powered Water Purification Methods