Opportunities and challenges of targeting cGAS–STING in cancer
Changzheng Lu, Wenyan Wang, Yang-Xin Fu
Topics & Concepts
Immune systemCancerSignal transductionMedicineInterferonCancer researchInflammationSignalling pathwaysGuanosineCytokineImmunologyCancer treatmentGuanosine monophosphateBiologyMechanism (biology)BioinformaticsHedgehog signaling pathwaySuppressor of cytokine signallingPathway analysisPathologicalGeneSignallingImmunotherapyInterferon type Iinterferon and immune responsesInflammasome and immune disordersCytokine Signaling Pathways and Interactions