Apoptosis induction, PARP-1 inhibition, and cell cycle analysis of leukemia cancer cells treated with novel synthetic 1,2,3-triazole-chalcone conjugates
Esraa M. Othman, Eman A. Fayed, Ebtehal M. Husseiny, Hamada S. Abulkhair
Topics & Concepts
ApoptosisChemistryChalconeLeukemiaCell cycleCancer researchCancer cellStaurosporineCytotoxicityCell cycle checkpointCancerPoly ADP ribose polymeraseIn vitroPharmacologyBiochemistryImmunologyBiologyStereochemistryEnzymeGeneticsPolymeraseProtein kinase CClick Chemistry and ApplicationsSynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds