Evolution of Antimicrobial Resistance Levels of ESKAPE Microorganisms in a Peruvian IV-Level Hospital
Wilfredo Flores-Paredes, Néstor Luque, Roger Albornoz, Nayade Rojas, Manuel Espinoza, María J. Pons, Joaquı́m Ruiz
Abstract
BACKGOUND: spp.) are a frequent cause of severe infection, ranking among the most relevant causes of hospital infections. In Peru, few studies, often focused in a single ESKAPE microorganism, have been performed, but none providing an overall and comprehensive long-time analysis of the antibiotic resistance of ESKAPE microorganisms. In the present study, the evolution of antimicrobial resistance levels of ESKAPE microorganisms isolated during 2009 - 2010 (Period 1) and 2012 - 2014 (Period 2) in a IV-level hospital in Lima was analyzed. MATERIALS AND METHODS: ) were determined using automatic methods. RESULTS: showed significantly increased resistance to different cephalosporins, carbapenems and amoxicillin plus sulbactam. CONCLUSION: clone in the ICU is suspected. The isolation of ESKAPE and levels of antibiotic resistance levels have reduced over time.