Nucleoside modifications of in vitro transcribed mRNA to reduce immunogenicity and improve translation of prophylactic and therapeutic antigens
Mohamad‐Gabriel Alameh, Drew Weissman
Topics & Concepts
ImmunogenicityRNATranscription (linguistics)Messenger RNAInnate immune systemNucleaseImmune systemTranslation (biology)BiologyIn vitroCell biologyChemistryGeneBiochemistryImmunologyPhilosophyLinguisticsRNA Interference and Gene Deliveryinterferon and immune responsesRNA and protein synthesis mechanisms