Oncolytic avian reovirus σA‐modulated fatty acid metabolism through the PSMB6/Akt/SREBP1/acetyl-CoA carboxylase pathway to increase energy production for virus replication
Chao‐Yu Hsu, Yun-Han Chen, Wei‐Ru Huang, Jing-Wen Huang, I‐Chun Chen, Yu-Kang Chang, Chi-Young Wang, Ching‐Dong Chang, Tsai‐Ling Liao, Brent L. Nielsen, Hung‐Jen Liu
Topics & Concepts
Sterol regulatory element-binding proteinFatty acid synthesisFatty acid synthaseCeruleninBiologyFatty acidFatty acid metabolismBiochemistryPyruvate carboxylaseCell biologyTranscription factorEnzymeGenePeroxisome Proliferator-Activated ReceptorsCancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism