A caveat to common hemicyanine dye components and their resolution
Hyeon Jin Park, Chang Wook Song, Sourav Sarkar, Yong Woong Jun, Ye Jin Reo, Mingchong Dai, Kyo Han Ahn
Abstract
Near-infrared-emitting hemicyanine dyes are widely used in activatable fluorescent probes for various biological analytes; however, they are chemically unstable and show photoinstability, as shown here with naphthalene-based hemicyanines containing a typical hemicyanine moiety, 2-indolium. These issues can be resolved with a 4-pyridinium derivative, which also has good two-photon imaging capability.
Topics & Concepts
Resolution (logic)ChemistryComponent (thermodynamics)Computer scienceProgramming languagePhysicsThermodynamicsPhotoreceptor and optogenetics researchMolecular Sensors and Ion DetectionAdvanced Fluorescence Microscopy Techniques