Depletion of macrophages deteriorates bisphosphonate-related osteonecrosis of the jaw-like lesions in mice
Ryohei Kozutsumi, Shinichiro Kuroshima, Farah A. Al‐Omari, Hiroki Hayano, Kazunori Nakajima, Hiroe Kakehashi, Takashi Sawase
Topics & Concepts
Osteonecrosis of the jawMedicineMacrophageBisphosphonateCD163PathologyInfiltration (HVAC)Soft tissueDental alveolusBisphosphonate-associated osteonecrosis of the jawMacrophage polarizationSystemic administrationOsteoclastOsteoporosisChemistryInternal medicineDentistryIn vivoBiologyReceptorIn vitroThermodynamicsBiochemistryPhysicsBiotechnologyBone health and treatmentsBone and Joint DiseasesCancer Diagnosis and Treatment