Metal-free visible-light-driven cascade cyclization reaction to synthesize 2-oxindoles <i>via</i> benzoyl and phenylsulfinyl radicals with acrylamide derivatives
Xin Sun, Jing-Ping Zhu, Qing-Chuang Qiu, Yali He, Da-rong Hu, Xin-Ling Li, Gui-Ping Lu, Yinghui Yuan, Xiang-Fei Zhang, Xiaobo Xu, Miao Yu, Bin Wu
Abstract
benzoyl and phenylsulfinyl radicals with acrylamide derivatives is reported, respectively. Extensive studies, including gram-scale, radical capture and isotope experiments, were performed to indicate that the reaction may involve a radical process.
Topics & Concepts
ChemistryRadicalAcrylamideCascadePhotochemistryCombinatorial chemistryMetalOrganic chemistryPolymerChromatographyCopolymerSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods