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In situ production and precise release of bioactive GM-CSF and siRNA by engineered bacteria for macrophage reprogramming in cancer immunotherapy

Yaxin Wang, Yali Fan, Xinyu Zhang, Jing Liu, Dawei Sun, Lianyue Li, Guijie Bai, Xinyu Liu, Jun Kang, Yingying Zhang, Hanjie Wang, Yingying Zhang, Hanjie Wang

2024Biomaterials26 citationsDOI

Topics & Concepts

ReprogrammingMacrophageCancer immunotherapyImmunotherapyMaterials scienceIn situCancerBacteriaCancer researchMicrobiologyImmune systemBiologyCellImmunologyIn vitroChemistryBiochemistryGeneticsOrganic chemistryCancer Research and TreatmentsVirus-based gene therapy researchNanoplatforms for cancer theranostics
In situ production and precise release of bioactive GM-CSF and siRNA by engineered bacteria for macrophage reprogramming in cancer immunotherapy | Litcius