BSA-encapsulated cyclometalated iridium complexes as nano-photosensitizers for photodynamic therapy of tumor cells
Yao−Zhong Xu, Xiang Wang, Kang Song, Jun Du, Jinliang Liu, Yuqing Miao, Yuhao Li
Abstract
generation capacity, and cellular uptake performance, the results show that Ir1@BSA has the best photodynamic therapeutic effect on 4T1 tumor cells. This study provides an effective research basis for the further design of new nano-photosensitizers.
Topics & Concepts
Photodynamic therapySinglet oxygenChemistryPhotosensitizerIridiumBovine serum albuminLigand (biochemistry)PyrazineCombinatorial chemistryNano-BiophysicsPhotochemistryStereochemistryBiochemistryReceptorOxygenOrganic chemistryMaterials scienceCatalysisBiologyComposite materialNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesLuminescence and Fluorescent Materials