Low-dose mono(2-ethylhexyl) phthalate promotes ovarian cancer development through PPARα-dependent PI3K/Akt/NF-κB pathway
Jing Leng, Hongyi Li, Yuequn Niu, Kelie Chen, Xiaoyu Yuan, Hanwen Chen, Zhiqin Fu, Lihuan Zhang, Fang Wang, Chaoyi Chen, Paul Héroux, Jun Yang, Xinqiang Zhu, Weiguo Lü, Dajing Xia, Yihua Wu
Topics & Concepts
PI3K/AKT/mTOR pathwayOvarian cancerCancer researchProtein kinase BPhthalatePeroxisome proliferator-activated receptorGene knockdownMetastasisEndocrinologyInternal medicineChemistryBiologySignal transductionCancerMedicineCell biologyReceptorApoptosisBiochemistryOrganic chemistryPeroxisome Proliferator-Activated ReceptorsCancer, Lipids, and MetabolismMetabolism, Diabetes, and Cancer