“COVID toes”: A true viral phenomenon or a diagnosis without a leg to stand on?
Jia C. Gao, Alisen Huang, Ankuri Desai, Bijan Safai, Shoshana Marmon
Abstract
"COVID toes" is the colloquial name of chilblain-like lesions thought to be a sequela of COVID-19 infection. Over two years and approximately 300 publications later, this association remains controversial. Here, we summarize key clinical, serological, biological, histological, and immunological evidence that supports and rejects this relationship and discuss alternate theories underlying the pathogenesis of chilblain-like lesions.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)Sequela2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedicineViral infectionPhenomenonVirologyPathologyPhilosophyVirusDiseaseSurgeryEpistemologyInfectious disease (medical specialty)OutbreakDermatological and COVID-19 studiesParvovirus B19 Infection StudiesStreptococcal Infections and Treatments