Design of PROTACs utilizing the E3 ligase GID4 for targeted protein degradation
Yanran Li, Kaiwen Bao, Jiyue Sun, Ruixin Ge, Qiqing Zhang, Bing Zhang, Xiaojie Yan, J. G. Li, Fengying Shi, Meiling Zhang, Jinzhi Zang, Min Liu, Jun Zhou, Wenyi Mi, Songbo Xie, Dongxing Chen, Lei Shi, Dong Cheng
Topics & Concepts
Ubiquitin ligaseProtein degradationDegradation (telecommunications)Ubiquitin-Protein LigasesDNA ligaseCell biologyUbiquitinChemistryComputational biologyBiophysicsBiochemistryBiologyComputer scienceDNATelecommunicationsGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis