Visible-Light-Mediated Three-Component Radical Iodosulfonylative Cyclization of Enynes
Qi Cheng, Fengrong Zhang, Xiaoyun Chen, Ying Han, Chao‐Guo Yan, Yaocheng Shi, Hong Hou, Shaoqun Zhu
Abstract
An efficient three-component radical iodosulfonylative cyclization of enynes is described. The visible-light irradiation of iodoform with sulfinates enables sulfonyl radical generation under catalyst- and oxidant-free conditions and triggers the radical addition, cyclization and iodination cascade reactions, giving various vinyl iodide containing sulfones in moderate to good yields.
Topics & Concepts
ChemistryRadical cyclizationIodoformSulfonylIodideCatalysisPhotochemistryCascadeHalogenationVisible spectrumRadicalFree-radical additionComponent (thermodynamics)Organic chemistryCombinatorial chemistryAlkylOptoelectronicsPhysicsChromatographyThermodynamicsSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods