J-domain proteins: From molecular mechanisms to diseases
Jarosław Marszałek, Paolo De Los Rios, Douglas Cyr, Matthias P. Mayer, Vasista Adupa, Claes Andréasson, Gregory L. Blatch, Janice E.A. Braun, Jeffrey L. Brodsky, Bernd Bukau, J. Paul Chapple, Charlotte Conz, Sébastien Dementin, Pierre Genevaux, Olivier Genest, Pierre Goloubinoff, Jason E. Gestwicki, Colin M. Hammond, Justin K. Hines, Koji Ishikawa, Łukasz A. Joachimiak, Janine Kirstein, Krzysztof Liberek, Dejana Mokranjac, Nadinath B. Nillegoda, Carlos H.I. Ramos, Mathieu E. Rebeaud, David Ron, Sabine Rospert, Chandan Sahi, Reut Shalgi, Bartłomiej Tomiczek, Ryo Ushioda, Elizaveta Ustyantseva, Yihong Ye, Maciej Żylicz, Harm H. Kampinga
Abstract
J-domain proteins (JDPs) are the largest family of chaperones in most organisms, but much of how they function within the network of other chaperones and protein quality control machineries is still an enigma. Here, we report on the latest findings related to JDP functions presented at a dedicated JDP workshop in Gdansk, Poland. The report does not include all (details) of what was shared and discussed at the meeting, because some of these original data have not yet been accepted for publication elsewhere or represented still preliminary observations at the time.