Litcius/Paper detail

Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective

Radhika Mathur, Qixuan Wang, Patrick G. Schupp, Ana Nikolić, Stephanie Hilz, Chibo Hong, Nadia Grishanina, Darwin Kwok, Nicholas Stevers, Qiushi Jin, Mark W. Youngblood, Lena Stasiak, Ye Hou, Juan Wang, Takafumi N. Yamaguchi, Marisa Lafontaine, Anny Shai, Ivan Smirnov, David A. Solomon, Susan M. Chang, Shawn L. Hervey‐Jumper, Mitchel S. Berger, Janine Lupo, Hideho Okada, Joanna J. Phillips, Paul C. Boutros, Marco Gallo, Michael C. Oldham, Feng Yue, J Costello

2024Cell200 citationsDOIOpen Access PDF

Topics & Concepts

BiologyGenetic heterogeneityEpigenomicsGlioblastomaBrain tumorTumor heterogeneityLineage (genetic)Somatic evolution in cancerComputational biologyEvolutionary biologyGliomaCancer researchGeneGeneticsPathologyPhenotypeDNA methylationCancerGene expressionMedicineSingle-cell and spatial transcriptomicsCell Image Analysis TechniquesGlioma Diagnosis and Treatment