Synthesis, molecular modeling Insights, and anticancer assessment of novel polyfunctionalized Pyridine congeners
Mohamed G. Abouelenein, Ahmed A. El‐Rashedy, Hanem M. Awad, Ahmed F. El‐Farargy, Ibrahim F. Nassar, Amr Nassrallah
Topics & Concepts
ChemistryDownregulation and upregulationPyridineAllosteric regulationIn silicoApoptosisGeneStereochemistryDocking (animal)Caspase 3Gene expressionBiochemistryProgrammed cell deathEnzymeMedicinal chemistryNursingMedicineSynthesis and biological activityComputational Drug Discovery MethodsCancer therapeutics and mechanisms