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Investigation of the detoxification effect of <i>licorice</i> on <i>Semen Strychni</i>-induced acute toxicity in rats using a HPLC-Q-TOF/MS-based metabolomics approach

Yalan Xiang, Chao Wang, Jing Wen, Min Zhang, Xiaoyu Duan, Lu Wang, Miao Yan, LI Huan-de, Pingfei Fang

2020RSC Advances10 citationsDOIOpen Access PDF

Abstract

Biomarkers and metabolomic pathway provide an integral understanding for the acute toxicity of <italic>Semen Strychni</italic> and the detoxification effect of <italic>licorice</italic>.

Topics & Concepts

Detoxification (alternative medicine)ChemistryChromatographySemenAcute toxicityMetabolomicsPharmacologyToxicityMedicineOrganic chemistryAndrologyPathologyAlternative medicinePharmacological Effects of Natural CompoundsGinseng Biological Effects and ApplicationsPlant-based Medicinal Research
Investigation of the detoxification effect of <i>licorice</i> on <i>Semen Strychni</i>-induced acute toxicity in rats using a HPLC-Q-TOF/MS-based metabolomics approach | Litcius