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Combining Green Light-Activated Photoiniferter RAFT Polymerization and RAFT Dispersion Polymerization for Graft Copolymer Assemblies

Shuaiqi Yang, Li Zhang, Ying Chen, Jianbo Tan

2022Macromolecules29 citationsDOI

Abstract

Although reversible addition–fragmentation chain transfer (RAFT) dispersion polymerization-induced self-assembly (PISA) has become one of the most attractive methods for the synthesis block copolymer assemblies, the synthesis of well-defined graft copolymer assemblies has rarely been reported. Herein, multifunctional macro-RAFT agents with well-defined structures were synthesized by green light-activated photoiniferter RAFT polymerization and subsequently used in RAFT dispersion polymerization for the synthesis of graft copolymers as well as graft copolymer assemblies. A direct comparison between RAFT-PISA behaviors of linear block copolymers and graft copolymers was conducted by using a monofunctional macro-RAFT agent and a multifunctional macro-RAFT agent, respectively. Transmission electron microscopy (TEM) analysis demonstrated that the structure of graft copolymers facilitated the creation of polymer nanoparticles with higher-order morphologies. Multifunctional macro-RAFT agents with different distributions of RAFT groups were also synthesized via a two-step photoiniferter RAFT polymerization. The influence of the distribution of solvophobic side chains on the RAFT-PISA process as well as graft copolymer assemblies was also investigated. We anticipate that this work should not only shed some light on the synthesis of well-defined graft copolymers and graft copolymer assemblies but also be useful to understand the mechanism RAFT-PISA of graft copolymers.

Topics & Concepts

RaftCopolymerChain transferReversible addition−fragmentation chain-transfer polymerizationPolymerizationPolymer chemistryMaterials scienceDispersion polymerizationLiving polymerizationChemistryPolymerRadical polymerizationComposite materialAdvanced Polymer Synthesis and CharacterizationNanoparticle-Based Drug Deliverybiodegradable polymer synthesis and properties