Hypoestins A–D: highly modified fusicoccane diterpenoids with promising Ca<sub>v</sub>3.1 calcium channel inhibitory activity from <i>Hypoestes purpurea</i>
Xing‐De Wu, Lin‐Fen Ding, Wenyan Li, Bin Cheng, Tie Lei, Haofeng Zhou, Qin‐Shi Zhao
Abstract
Four highly modified fusicoccane diterpenoids with two unreported carbon skeletons, hypoestins A–D (1–4), were isolated and characterized from Hypoestes purpurea .
Topics & Concepts
ChemistryCalcium channelStereochemistryCalciumInhibitory postsynaptic potentialOrganic chemistryNeuroscienceBiologyPhytochemistry and biological activities of Ficus speciesTraditional and Medicinal Uses of AnnonaceaePhytochemistry and Bioactive Compounds