Macrolide-Resistant <i>Bordetella pertussis</i>, Vietnam, 2016−2017
Kazunari Kamachi, Hong Thi Duong, Anh Duc Dang, To Van Hai, Do Do, Kentaro Koide, Nao Otsuka, Keigo Shibayama, Ha Thi Thu Hoang
Abstract
Macrolide-resistant Bordetella pertussis emerged in Vietnam during 2016-2017. Direct analyses of swab samples from 10 patients with pertussis revealed a macrolide-resistant mutation, A2047G, in the 23S rRNA. We identified the MT104 genotype of macrolide-resistant B. pertussis (which is prevalent in mainland China) and its variants in these patients.
Topics & Concepts
Bordetella pertussisMicrobiologyWhooping coughVirologyGram-negative bacterial infectionsMedicinePathogenic organismBordetellaBiologyAntibioticsBacteriaVaccinationGeneticsBacterial Infections and VaccinesInfectious Encephalopathies and EncephalitisInfective Endocarditis Diagnosis and Management