Plasmon-Enhanced Electrochemiluminescence of PTP-Decorated Eu MOF-Based Pt-Tipped Au Bimetallic Nanorods for the Lincomycin Assay
Jingxian Li, Mengyu Luo, Can Jin, Penghui Zhang, Hongfen Yang, Ren Cai, Weihong Tan
Abstract
Plasmonic bimetal nanostructures can be employed to amplify electrochemiluminescence (ECL) signals. In this work, a high-performance ECL platform was constructed using a europium metal-organic framework (MOF) as a luminophore and Au-Pt bimetallic nanorods (NRs) as a plasma source. Due to the SPR effect of Au-Pt NRs, the aptasensor exhibits 2.6-fold ECL intensity compared to that of pure polyaniline (PANI)-decorated perylene tetracarboxylic dianhydride (PTCA)/Eu MOF. Moreover, decoration with PTP greatly enhances the conductivity and stability of Eu MOF, resulting in sizeable plasmon-enhanced electrochemical luminescence. The as-designed plasmon-enhanced ECL aptasensor displayed highly sensitive detection for lincomycin (Lin). The as-proposed aptasensor could quantify Lin from 0.1 mg/mL to 0.1 ng/mL with a limit of detection (LOD) of 0.026 ng/mL.