Separation of phosphorothioate oligonucleotide impurities by WAX HPLC under high organic content elution conditions
Stilianos G. Roussis, Claus Rentel
Topics & Concepts
ElutionWaxChemistryChromatographyOligonucleotideHydrophilic interaction chromatographyIon exchangeIonic bondingImpurityPhase (matter)Analytical Chemistry (journal)High-performance liquid chromatographyIonOrganic chemistryDNABiochemistryAnalytical Chemistry and ChromatographyMicrofluidic and Capillary Electrophoresis ApplicationsDNA and Nucleic Acid Chemistry