Synthesis, characterization, molecular docking, and anticancer activities of new 1,3,4-oxadiazole-5-fluorocytosine hybrid derivatives
Az‐eddine El Mansouri, Saida Lachhab, Ali Oubella, Ahmad Mehdi, Johan Neyts, Dirk Jochmans, Winston Chiu, Laura Vangeel, Steven De Jonghe, Hamid Morjani, Mustapha Ait Ali, Mohamed Zahouily, Yogesh S. Sanghvi, Hassan B. Lazrek
Topics & Concepts
ChemistryOxadiazoleDocking (animal)Cell cycle checkpointApoptosisPyrimidineStereochemistryCell cultureCell cycleCytotoxicityIn vitroCombinatorial chemistryBiochemistryOrganic chemistryGeneticsBiologyMedicineNursingHIV/AIDS drug development and treatmentSynthesis and biological activityCancer therapeutics and mechanisms