Iron–cobalt-catalyzed heterotrimerization of alkynes and nitriles to polyfunctionalized pyridines
Yufang Xie, Chengjuan Wu, Changhao Jia, Chen‐Ho Tung, Wenguang Wang
Abstract
The iron(<sc>ii</sc>)–cobalt(<sc>ii</sc>) co-catalyzed heterotrimerization of alkynes and nitriles enables the synthesis of 2,3,4,5,6-pentafunctionalized pyridines in a single step.
Topics & Concepts
ChemistryCobaltCatalysisCombinatorial chemistryMedicinal chemistryNitrileOrganic chemistryCatalytic C–H Functionalization MethodsSulfur-Based Synthesis TechniquesCatalytic Alkyne Reactions