The Salivary Microbiota, Cytokines, and Metabolome in Patients with Ankylosing Spondylitis Are Altered and More Proinflammatory than Those in Healthy Controls
Longxian Lv, Huiyong Jiang, Yan Ren, Danyi Xu, Kaicen Wang, Qiangqiang Wang, Xiaoxiao Chen, Lanjuan Li
Abstract
. Reducing the levels of salivary microbes can significantly reduce the hazardous materials present in the saliva of AS patients. Our results provide a new perspective on the potential role of salivary microbes, cytokines, and hazardous compounds in the pathogenesis and treatment of AS.
Topics & Concepts
Ankylosing spondylitisProinflammatory cytokineMetabolomeImmunologyGut floraMedicineSpondylitisPathogenesisPopulationInternal medicineInflammationEnvironmental healthMetaboliteSpondyloarthritis Studies and TreatmentsPsoriasis: Treatment and PathogenesisFibromyalgia and Chronic Fatigue Syndrome Research