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Enantioselective reductive allylic alkylation enabled by dual photoredox/palladium catalysis

Sheng Tang, Hong‐Hao Zhang, Shouyun Yu

2023Chemical Communications16 citationsDOIOpen Access PDF

Abstract

) bonds under mild reaction conditions. Mechanistic studies suggest that this reaction involves radical pathways and a chiral Pd complex enables the control of the regio- and enantioselectivities.

Topics & Concepts

PalladiumTsuji–Trost reactionEnantioselective synthesisAlkylationCatalysisCombinatorial chemistryChemistryAllylic rearrangementDual (grammatical number)Organic chemistryLiteratureArtRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions