Easily accessed nitroquinolones exhibiting potent and selective anti-tubercular activity
Phelelisiwe S. Dube, Lesetja J. Legoabe, Audrey Jordaan, Omobolanle J. Jesumoroti, Tendamudzimu Tshiwawa, Digby F. Warner, Richard M. Beteck
Topics & Concepts
ChemistryNitroDocking (animal)StereochemistryMoietyQuinoloneAmine gas treatingBiological activityStructure–activity relationshipActive siteCombinatorial chemistryIn vitroEnzymeAntibioticsBiochemistryOrganic chemistryNursingAlkylMedicineCancer therapeutics and mechanismsSynthesis and biological activityTuberculosis Research and Epidemiology