Alkylated monoterpene indole alkaloid derivatives as potent P-glycoprotein inhibitors in resistant cancer cells
David Cardoso, Annamária Kincses, Márta Nové, Gabriella Spengler, Silva Mulhovo, João Aires‐de‐Sousa, Daniel J. V. A. dos Santos, Maria‐José U. Ferreira
Topics & Concepts
ChemistryIndole testP-glycoproteinStereochemistryLipophilicityMultiple drug resistanceCytotoxicityMonoterpeneDoxorubicinAlkaloidIn vitroBiochemistryPharmacologyChemotherapyBiologyGeneticsAntibioticsDrug Transport and Resistance MechanismsAlkaloids: synthesis and pharmacologyBerberine and alkaloids research