Litcius/Paper detail

Organic photosensitizers: from molecular design to phototheranostics

Tian Zhang, Xinyu Qu, Jinjun Shao, Xiaochen Dong

2025Chemical Society Reviews85 citationsDOI

Abstract

designing TME-activatable photosensitizers. Additionally, this review highlights emerging applications in precision oncotherapy, antimicrobial therapy, and afterglow imaging diagnostics. Moreover, the perspectives and challenges of the molecular design and phototheranostics of organic photosensitizers are discussed. This review aims to bridge fundamental research with clinical translation challenges, providing strategic insights for advancing next-generation organic photosensitizers.

Topics & Concepts

Photodynamic therapyRational designMolecular engineeringNanotechnologyComputer scienceBiochemical engineeringChemistryMaterials scienceEngineeringOrganic chemistryNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesLuminescence and Fluorescent Materials