Systemic therapy for gastric cancer: Perioperative strategies and beyond
Christopher Cann, Kristen K. Ciombor
Abstract
Each year, gastric cancer claims the lives of hundreds of thousands of patients worldwide. Despite surgical resection, the risk of residual disease, micrometastatic disease, and disease recurrence remain elevated. Herein, we review systemic therapy strategies in the neoadjuvant, adjuvant, and metastatic settings, including novel uses of immunotherapy, targeted therapies and cytotoxic chemotherapies, for the treatment of gastric cancer.
Topics & Concepts
MedicinePerioperativeCancerDiseaseImmunotherapyNeoadjuvant therapySystemic therapyOncologyAdjuvantInternal medicineAdjuvant therapyTargeted therapySurgeryBreast cancerGastric Cancer Management and OutcomesGastrointestinal Tumor Research and TreatmentMetastasis and carcinoma case studies