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Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells

Jonathon M. Muncie, Nadia M.E. Ayad, Johnathon N. Lakins, Xufeng Xue, Jianping Fu, Valerie M. Weaver

2020Developmental Cell146 citationsDOIOpen Access PDF

Topics & Concepts

GastrulationMesodermCell biologyMorphogenBiologyEmbryonic stem cellNODALWnt signaling pathwayCell fate determinationEmbryogenesisExtracellular matrixNodal signalingMorphogenesisEmbryoAnatomySignal transductionGeneticsTranscription factorGeneCellular Mechanics and InteractionsPluripotent Stem Cells Research3D Printing in Biomedical Research
Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells | Litcius