Litcius/Paper detail

The role of non-affine deformations in the elastic behavior of the cellular vertex model

Michael F. Staddon, Arthur Hernandez, Mark J. Bowick, Michael Moshe, M. Cristina Marchetti

2023Soft Matter20 citationsDOIOpen Access PDF

Abstract

(6), it is geometrically impossible for any cell to realize the preferred area and perimeter simultaneously, and the tissue is in an incompatible rigid solid state. Using a mean-field approach, we present a complete analytical calculation of the linear elastic moduli of an ordered vertex model. We analyze a relaxation step that includes non-affine deformations, leading to a softer response than previously reported. The origin of the vanishing shear and Young's moduli in the compatible state is the presence of zero-energy deformations of cell shape. The bulk modulus exhibits a jump discontinuity at the transition and can be lower in the rigid state than in the fluid-like state. The Poisson's ratio can become negative which lowers the bulk and Young's moduli. Our work provides a unified treatment of linear elasticity for the vertex model and demonstrates that this linear response is protocol-dependent.

Topics & Concepts

PerimeterVertex (graph theory)ModuliVertex modelShear modulusAffine transformationPoisson's ratioGeometryLinear elasticityElasticity (physics)MathematicsPoisson distributionMathematical analysisElastic energyModulusElastic modulusPhysicsCombinatoricsFinite element methodQuantum mechanicsThermodynamicsStatisticsGraphCellular Mechanics and Interactions3D Printing in Biomedical ResearchMicrotubule and mitosis dynamics