Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders
Stefano Fiorucci, Valentina Sepe, Michele Biagioli, Bianca Fiorillo, Pasquale Rapacciuolo, Eleonora Distrutti, Angela Zampella
Topics & Concepts
Farnesoid X receptorPregnane X receptorG protein-coupled bile acid receptorReceptorNuclear receptorSteatohepatitisBiologyAgonistG protein-coupled receptorLiver X receptorChemistryInternal medicineBiochemistryFatty liverMedicineTranscription factorDiseaseGeneDrug Transport and Resistance MechanismsLiver Disease Diagnosis and TreatmentPediatric Hepatobiliary Diseases and Treatments